| | Type of Owner | Securities Owned | As Insider in other Companies | Date Last Transaction |
|---|
| | CFO, Vice President | 56,515,000 | 0 | 2011-04-13 |
| | President, CEO | 21,998,900 | 0 | 2016-07-01 |
| | President, CEO, Dir | 5,811,250 | 2 | 2014-06-30 |
| | President, CEO, Dir | 4,649,700 | 1 | 2011-03-15 |
| | Dir | 2,847,500 | 1 | 2017-10-10 |
| | Dir | 2,145,900 | 0 | 2017-10-10 |
| | VP Business Development | 2,054,150 | 0 | 2011-03-15 |
| | Dir | 1,958,350 | 7 | 2017-10-10 |
| | Dir | 1,907,700 | 2 | 2017-10-10 |
| | Dir | 1,801,950 | 0 | 2017-10-10 |
| | Dir | 1,734,500 | 0 | 2017-10-10 |
| | Dir | 1,566,950 | 0 | 2017-10-10 |
| | CEO, Dir, President | 859,032 | 0 | 2025-01-10 |
| | Cont, Principlw Acctg Officer | 703,250 | 0 | 2011-03-15 |
| | Chief Medical Officer | 425,150 | 0 | 2016-07-01 |
| | SVP, Chief Development Officer | 309,628 | 1 | 2025-01-10 |
| | CFO | 299,062 | 0 | 2025-01-10 |
| | Legal, VP | 287,500 | 0 | 2010-01-20 |
| | Dir | 250,000 | 2 | 2014-01-23 |
| | Principal Accounting Officer | 250,000 | 0 | 2011-12-07 |
| | Chief Medical Officer, EVP | 123,050 | 1 | 2014-06-30 |
| | Corp. Sec., EVP, Gen. Counsel | 117,225 | 0 | 2024-01-22 |
| | Chief Commercial Officer | 40,918 | 0 | 2024-01-22 |
| | Dir | 23,082 | 0 | 2025-01-10 |
| | Dir | 22,900 | 2 | 2025-01-10 |
| | Dir | 22,900 | 2 | 2025-01-10 |
| | Dir | 22,900 | 2 | 2025-01-10 |
| | Dir | 21,000 | 1 | 2025-01-10 |
| | 10%own | 0 | 0 | 2010-12-29 |
| | Dir | 0 | 0 | 2016-10-22 |
| | General Counsel, VP | 0 | 0 | 2014-07-18 |
| | General Counsel | 0 | 0 | 2015-06-15 |
| | Interim CFO | 0 | 0 | 2017-12-19 |
| | Treasurer, CFO | 0 | 1 | 2018-04-10 |
| | Chief Medical Officer | 0 | 4 | 2012-01-22 |
| | Technology Development, VP | 0 | 0 | 2010-03-31 |
| | Chief Medical Officer, SVP | 0 | 0 | 2017-12-19 |
| | CRO, SVP | 0 | 0 | 2017-12-19 |
